E6 e7 viral messenger rna11/28/2023 However, the sensitivity of the real-time NASBA assay was lower than that of HPV DNA testing (41.1% vs. Previous data has shown that the real-time NASBA assay has higher clinical specificity than HPV DNA testing (97.1% vs. For this reason, HPV tests targeting the E6 and E7 mRNA of five oncogenic HPV strains (HPV genotypes 16, 18, 31, 33, and 45), which are known to be responsible for the oncogenesis of cervical cancer, have been commercialized using a real-time nucleic acid sequence based amplification (NASBA) assay. Electronic address: research has shown that oncogenic human papillomavirus (HPV) DNA, which is currently used in the screening and diagnosis of cervical cancer, can be detected not only in high-grade cervical lesions, but also in low-grade cervical lesions and normal tissues. Electronic address: 10 M&D, Inc., Wonju Eco Environmental Technology Center, Wonju, Gangwon 200-722, Republic of Korea. 9 Department of Pathology, Yonsei University Wonju College of Medicine, Wonju, Gangwon 220-701, Republic of Korea.Electronic address: 1 Department of Pathology, Yonsei University Wonju College of Medicine, Wonju, Gangwon 220-701, Republic of Korea. 8 Department of Clinical Laboratory Science, College of Health Sciences, Catholic University of Pusan, Pusan.7 Institute of Lifestyle Medicine, Wonju College of Medicine, Yonsei University, Wonju, Gangwon 220-701, Republic of Korea.6 Department of Biomedical Laboratory Science, Songho College, Hoengseong, Gangwon 225-704, Republic of Korea.5 Department of Biomedical Laboratory Science, College of Health Sciences, Yonsei University, Wonju, Gangwon 220-710, Republic of Korea Institute for Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea.4 Department of Biomedical Laboratory Science, College of Health Sciences, Yonsei University, Wonju, Gangwon 220-710, Republic of Korea Department of Clinical Laboratory Science, Hyejeon College, Hongseong, Chungnam 350-702, Republic of Korea.3 M&D, Inc., Wonju Eco Environmental Technology Center, Wonju, Gangwon 200-722, Republic of Korea.2 Department of Biomedical Laboratory Science, College of Health Sciences, Yonsei University, Wonju, Gangwon 220-710, Republic of Korea.1 Department of Pathology, Yonsei University Wonju College of Medicine, Wonju, Gangwon 220-701, Republic of Korea.
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